By Plamen Demirev,Todd R. Sandrin
In the final area century, advances in mass spectrometry (MS) were on the vanguard of efforts to map complicated organic platforms together with the human metabolome, proteome, and microbiome. All of those advancements have allowed MS to turn into a well-established molecular point expertise for microorganism characterization. MS has validated its significant virtue as a swift, exact, and comparatively cheap process for microorganism identity, in comparison to traditional phenotypic recommendations. within the final numerous years, purposes of MS for microorganism characterization in study, medical microbiology, counter-bioterrorism, nutrition defense, and environmental tracking were documented in millions of guides. Regulatory our bodies in Europe, the U.S., and in different places have authorized MS-based assays for infectious ailment diagnostics. As of mid-2015, greater than 3300 advertisement MS platforms for microorganism identity were deployed around the world in hospitals and scientific labs.
While past paintings has coated broader techniques in utilizing MS to signify microorganisms on the species point or above, this ebook specializes in strain-level and subtyping purposes. In twelve person chapters, innovators, leaders and practitioners within the box from all over the world have contributed to a complete evaluate of present and next-generation methods for MS-based microbial characterization on the subspecies and pressure degrees. Chapters contain up to date reference lists in addition to web-links to databases, prompt software program, and different worthy tools.
The emergence of latest, antibiotic-resistant traces of human or animal pathogens is of striking situation not just to the clinical and scientific groups, yet to most people in addition. advancements of novel MS-based assays for swift identity of traces of antibiotic-resistant microorganisms are reviewed within the booklet in addition. Microbiologists, bioanalytical scientists, infectious sickness experts, medical laboratory and public healthiness practitioners in addition to researchers in universities, hospitals, executive labs, and the pharmaceutical and biotechnology industries will locate this ebook to be a well timed and priceless resource.
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Extra info for Applications of Mass Spectrometry in Microbiology: From Strain Characterization to Rapid Screening for Antibiotic Resistance
Applications of Mass Spectrometry in Microbiology: From Strain Characterization to Rapid Screening for Antibiotic Resistance by Plamen Demirev,Todd R. Sandrin